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KMID : 0379520030190010029
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한국독성학회지
2003 Volume.19 No. 1 p.29 ~ p.31
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No Association of the Human Y Chromosome with Blood Pressure in Korean Male Population
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Kang Byung-Yong
Kim Seon-Jeong
Lee Kang-Oh
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Abstract
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It has been reported that the genetic variations in the Y chromosome has influence the blood pressure in some Caucasian male populations, but the effect in non-Caucasian population is unclear. In the present study, we examined the relationship between blood pressure and a HindIII RFLP of Y chromosome in 152 unrelated male individuals of ethnically homogeneous Korean origin. There were no significant differences in systolic and diastolic blood pressures between genotype groups, respectively. However, the frequency of A genotype in Korean population was much higher than those of Caucasian populations (P＜0.05). Therefore, the results of this study will con-tribute the better understanding the genetic characteristics of Y chromosome in Korean population.
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KEYWORD
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Blood pressure, Genotype and Y chromosome.
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